منابع مشابه
Metabolic Engineering of Bacteria
Metabolic glycoengineering is a technique introduced in the early 90s of the last century by Reutter et al.. It utilises the ability of cells to metabolically convert sugar derivatives with bioorthogonal side chains like azides or alkynes and by that incorporation into several glyco structures. Afterwards, the carbohydrates can be labelled to study their distribution, dynamics and roles in diff...
متن کاملMetabolic Engineering of Lactic Acid Bacteria for Production of Mannitol,
OF DOCTORAL DISSERTATION HELSINKI UNIVERSITY OF TECHNOLOGY P.O. BOX 1000, FI-02015 TKK http://www.tkk.fi Author Miia Helanto Name of the dissertation Metabolic engineering of lactic acid bacteria for production of mannitol, L-ribulose and L-ribose Manuscript submitted 12.9.2008 Manuscript revised 9.3.2009 Date of the defence 24.4.2009 Monograph Article dissertation (summary + original articles)...
متن کاملMetabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis.
Everyone who has ever tried to radically change metabolic fluxes knows that it is often harder to determine which enzymes have to be modified than it is to actually implement these changes. In the more traditional genetic engineering approaches 'bottle-necks' are pinpointed using qualitative, intuitive approaches, but the alleviation of suspected 'rate-limiting' steps has not often been success...
متن کاملThe logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering
Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health, biomanufacturing, and the environment. Over the last decade, SB promoted the construction of libraries of components enabling the fine-tuning of genetic ci...
متن کاملMetabolic engineering.
Metabolic engineering is the science that combines systematic analysis of metabolic and other pathways with molecular biological techniques to improve cellular properties by designing and implementing rational genetic modifications. As such, metabolic engineering deals with the measurement of metabolic fluxes and elucidation of their control as determinants of metabolic function and cell physio...
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ژورنال
عنوان ژورنال: Indian Journal of Microbiology
سال: 2011
ISSN: 0046-8991,0973-7715
DOI: 10.1007/s12088-011-0172-8